Senators centre Peter Regin is again sidelined with a left shoulder injury and won't be in the lineup on Saturday night, when the Columbus Blue Jackets visit Scotiabank Place (Photo by Jeff Vinnick/NHLI via Getty Images).

Peter Regin just can't seem to catch a break.

A good one, that is.

For the third time in six months, a left shoulder injury has forced the Ottawa Senators centre out of the lineup. While the Senators are still awaiting final test results, head coach Paul MacLean confirmed earlier today that Regin won't suit up Saturday night, when Ottawa faces off against the Columbus Blue Jackets at Scotiabank Place (7 p.m., CBC, Team 1200).

"I don't really want to speculate on (Regin's status), but he's not playing tomorrow, for sure," MacLean said following Senators practice at the Bell Sensplex. "We'll know more maybe by the end of the day today or tomorrow ... it wasn't like a great catastrophic hit or anything like that. It just seemed like a routine play."

Indeed, Regin's collision with Nik Antropov of the Winnipeg Jets during the first period of their game Thursday night at Scotiabank Place seemed rather innocent. But the Senators centre left the ice and didn't return for the rest of the night.

For the 25-year-old Regin, who missed the first two games of the regular schedule with a shoulder injury in the pre-season, it's the latest setback involving that particular part of his body. Back in March, he required season-ending surgery after injuring the same shoulder. Now it's happened for a third time and, MacLean admitted, "I would say it's a concern not only for us, but for him as well."

"I haven't had a chance to speak with him," added MacLean. "But every indication I've had from Gerry (Townend, the Senators' head athletic therapist) is that he's disappointed, which is only natural."

Defenceman Erik Karlsson, one of Regin's best friends on the team, suggested that's exactly the case for a centre who had given every indiciation he was primed for a strong season.

"So far, he's pretty (down), but he's still trying to keep it together," said Karlsson. "He's got a good personality, so I know he'll be fine ... He played great when he came here (this season). Then he got the shoulder problem going again and last night didn't help. We don't know how bad it is, but it's definitely hurting the team and hurting him as well. It's not something you want to see."

Anderson joins goaltenders' century club

When Senators netminder Craig Anderson shut down the Jets in Thursday's 4-1 victory at Scotiabank Place, he did a little more than give his teammates a lift. The 35-save effort also allowed the native of Park Ridge, Ill., to record his 100th career National Hockey League goaltending win.

Like with most everything else, Anderson took the milestone in stride when it was pointed out today.

"It just means I've been in the league for a few years," he said. "It's a good milestone to have when you're a goalie. To be able to reach 100 wins is an accomplishment in itself. I'm thankful for the guys in front of me who make the games like that happen."

Anderson kept the puck from the game, but has not plans for it just yet.

"Maybe I'll put a nail through it and hang it on the wall or something," he said with a grin.